Mouse anti CD38

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Main information

NameMouse anti CD38
Catalog number0381
Size100 μg
Price€ 195.00


More details

CategoryPrimary Antibodies
Long descriptionCD38 antigen is an integral membrane glycoprotein, M.W. 45 kD. The CD38 antigen is present on approximately all pre-B lymphocytes, plasma cells and thymocytes. CD38 antigen is also expressed on activated T Lymphocytes, NK Cells, monocytes, myeloblasts and erythroblasts. CD38 is co-expressed on CD34+ cells,but is not expressed on pluripotent stem cells. CD38 antigen is present on T and B lymphoblastic leukemia (ALL), Burkitts' lymphoma, multiple myeloma and acute myeloid leukemia (AML).
Antibody come fromn/a
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
CloneTME-2
Antigen-antibody binding interactionMouse anti CD38 Antibody
Antibody is raised inMouse
Antibody's reacts withHuman
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
Research interestCD Marker
ApplicationFlow Cytometry
Antibody's suited forPBMC: Add 10 µl of MAB/10^6 PBMC in 100 µl PBS. Mix gently and incubate for 15 minutes at 2¼ to 8¼C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. WHOLE BLOOD: Add 10 µl of MAB/100 µl of whole blood. Mix gently and incubate for 15 minutes at room temperature (20¼C). Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturerÕs instructions for Lysed Whole Blood and Immunofluorescence analysis with a flow cytometer or microscope.
Storage-20ºC
Relevant references1) CD38 Molecule: Structural and Biochemical Analysis on Human T Lymphocytes, Thymocytes and Plasma Cells. J. Immunol, 1990 Aug; 145(3):878-84. Alessio, M. Roggero, S.; Funaro, A. ; De Monte L.B.,: Peruzzi, L.; Geuna, M.; Malavasi,F. _x000B__x000B_2) Differences Amoung Mononuclear Cell Subpopulations in HIV Seropositive or Seronegative Homosexual and Heterosexual men as Determined by Four Color Flow Cytometry. J. Acquir Immume Defic Syndr., 1990;3(8):747-56. Schnizlein-Bick, C.T.; Magier, M.R.; Jones, R.B.; Fife, K.H.; Katz, B., P.; Walker, E.B. _x000B__x000B_3) Quantitative Comparison of Myeloid Antigens on Five Lineages of Mature Peripheral Blood Cells. J. Leukoc Bio. 1990, Au;48(2):13848. Terstappen, L.W.; Hollander, Z.; Meiners, H.; Loken, M.R. _x000B__x000B_4) B-cell Surface Phenotypes of Proliferating Myeloma Cells: Target Antigens for Immunotherapy. Am. J. Hematol. 1990, Fe;33(2):1019, Chan, C.S; Wormsley, S.B.; Pierce, L. E.; Peter, J.B.; Schechter, G.P. _x000B__x000B_5) Interrelationships Between Serologic Markers of Immune Activation and T Lymphocyte Subsets in HIV Infection. J. Acquir Immune Defic Syndr. 1990;3(5):525-30. Prince, H.E.; Kleinman, S. Czaplicki, C.; John, J.; Williams, A.E. _x000B__x000B_6) Sequential Gererations of Hematopoietic Colonies Derived from Single Nonlineage-committed CD34+ CD38- Progenitor Cells. Blood 1991, Mar 1;77(6):1218-27. Terstappen, L.W.; huang, S.; Safford, M. Lansdorp, P.M.; Loken, M.R. _x000B__x000B_7) Involvement of Multilineage CD38 Molecule in a Unique Pathway of Cell Activation and Proliferation. J. Immunol, 1990 Oct 1;145(8):2390-6Funaro, A.; Spagnoli, G.C.; Ausiello, C.M.; Alessio, M.; Roggero, S.; Delia, D.; Zaccolo, M.; Malavasi, F. _x000B__x000B_8) Induction of CD4 and Susceptibility to HIV-1 Infection in Human CD8+ T Lymphocytes by Human Herpesvirus 6. Nat.349(6309): 5335, 1991. Lusso, P.; De Maria, A.; Malnati, M.; Lori, F.; DeRocco, S.E.;Baseler, M.; Gallo, R.C. _x000B__x000B_9) Circulating Antigen-Specific Suppressor T Cells in a Healthy Woman: Mechanism of Action and Isolation with a Monoclonal Antibody. Clin. Res. 29, 365a, 1981. Engleman, E. G.; Benike, C. J.; Evans, R.L _x000B__x000B_10) CD4 and CD8 Molecules Can Physically Associate with the Same T-cell Receptor. Proc. Nat. Acad. Sci. 1989, 86:10044.
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus