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| Name | Mouse anti B7.1 (extra-cellular domain) |
|---|---|
| Catalog number | 0861 |
| Size | 100 μg |
| Price | € 355.00 |
| Category | Primary Antibodies |
|---|---|
| Long description | Cell Distribution: CD86 antibody is rapidly induced on the surface of and is expressed at high levels on dendritic cells. It is also found on malignant Hodgkin and Reed-Sternberg (H-RS) cells in HodgkinÕs disease._x000B_Function: CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient costimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. |
| Antibody come from | Recombinant expressed extra-cellular domain of human CD86. |
| Other description | Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography |
| Clone | B72-H2 |
| Antigen-antibody binding interaction | Mouse anti B7.1 (extra-cellular domain) Antibody |
| Antibody is raised in | Mouse |
| Antibody's reacts with | Human |
| Antibody's reacts with these species | This antibody doesn't cross react with other species |
| Antibody's specificity | No Data Available |
| Research interest | CD Marker |
| Application | Flow Cytometry, Immunohistochemistry |
| Antibody's suited for | Antibody can be used for flow cytometry and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions. |
| Storage | -20ºC |
| Relevant references | 1. Chan, E.P.H., et al. 'Effects of titanium(IV) ions on human monocyte-derived dendritic cells.' Metallomics 2009, 1, 166-174. |
| Protein number | see ncbi |
| Warnings | This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. |
| Tissue | cellular |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Test | Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain. |
| Latin name | Mus musculus |