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| Name | Mouse anti CTLA-4 (extra-cellular domain) |
|---|---|
| Catalog number | 1521 |
| Size | 100 μg |
| Price | € 345.00 |
| Category | Primary Antibodies |
|---|---|
| Long description | CD152 is one of two ligands (the other CD28) for CD80 and CD86. CD152 acts as co-stimulatory molecule in eliciting T-cell help during antigen presentation. |
| Antibody come from | Recombinant extra-cellular domain of human CD152._x000B_ |
| Other description | Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography |
| Clone | AS32 |
| Antigen-antibody binding interaction | Mouse anti CTLA-4 (extra-cellular domain) Antibody |
| Antibody is raised in | Mouse |
| Antibody's reacts with | Human |
| Antibody's reacts with these species | This antibody doesn't cross react with other species |
| Antibody's specificity | No Data Available |
| Research interest | CD Marker |
| Application | Neutralization |
| Antibody's suited for | Neutralization. AS32 has been shown to block the interaction of soluble hCD152 with hCD80 |
| Storage | -20ºC |
| Relevant references | 1. Bastien, J.-P., et al. 'Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease.' Blood, 2010, 116, 4859-4869. |
| Protein number | see ncbi |
| Warnings | This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. |
| Tissue | cellular |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Test | Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain. |
| Latin name | Mus musculus |