Mouse anti CTLA-4 (extra-cellular domain)

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Main information

NameMouse anti CTLA-4 (extra-cellular domain)
Catalog number1521
Size100 μg
Price€ 345.00


More details

CategoryPrimary Antibodies
Long descriptionCD152 is one of two ligands (the other CD28) for CD80 and CD86. CD152 acts as co-stimulatory molecule in eliciting T-cell help during antigen presentation.
Antibody come fromRecombinant extra-cellular domain of human CD152._x000B_
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
CloneAS32
Antigen-antibody binding interactionMouse anti CTLA-4 (extra-cellular domain) Antibody
Antibody is raised inMouse
Antibody's reacts withHuman
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
Research interestCD Marker
ApplicationNeutralization
Antibody's suited forNeutralization. AS32 has been shown to block the interaction of soluble hCD152 with hCD80
Storage-20ºC
Relevant references1. Bastien, J.-P., et al. 'Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease.' Blood, 2010, 116, 4859-4869.
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Tissuecellular
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus