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| Name | Mouse anti p16 - ink4a |
|---|---|
| Catalog number | C170M |
| Size | 100 μg |
| Price | € 304.00 |
| Category | Primary Antibodies |
|---|---|
| Long description | The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. |
| Antibody come from | A recombinant full length p16 protein recognizing a 16kDa protein |
| Other description | Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography |
| Clone | DCS50.1 |
| Antigen-antibody binding interaction | Mouse anti p16 - ink4a Antibody |
| Antibody is raised in | Mouse |
| Antibody's reacts with | Human |
| Antibody's reacts with these species | This antibody doesn't cross react with other species |
| Antibody's specificity | No Data Available |
| Application | Western Blot, Immunoprecipitation, Immunohistochemistry |
| Antibody's suited for | Applications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6) |
| Storage | -20ºC |
| Relevant references | 1) J. Lukas et.al (1995) Nature., 375,503-506 _x000B__x000B_2) L. Aagaard et.al. (1995), Intl. J. of Cancer 61(1) 115-120 |
| Protein number | see ncbi |
| Warnings | This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Test | Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain. |
| Latin name | Mus musculus |