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| Name | Mouse anti c-myc |
|---|---|
| Catalog number | N115M |
| Size | 100 μg |
| Price | € 304.00 |
| Category | Primary Antibodies |
|---|---|
| Long description | Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa. |
| Antibody come from | Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells. |
| Other description | Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography |
| Clone | 33 |
| Antigen-antibody binding interaction | Mouse anti c-myc Antibody |
| Antibody is raised in | Mouse |
| Antibody's reacts with | Human, Mouse, Avian |
| Antibody's reacts with these species | This antibody doesn't cross react with other species |
| Antibody's specificity | No Data Available |
| Application | Western Blot, Immunoprecipitation, Immunohistochemistry |
| Antibody's suited for | Application: Western Blot, Immunoprecipitation (both with and without SDS), Immunofluorescence, Frozen Sections -- Myc is a labile protein, therefore preotease inhibitors should be used at all times. |
| Storage | -20ºC |
| Relevant references | 1) K. Alitala et. al. (1983) Proc. Natl. Acad. Sci., 80: 1707-1711 _x000B__x000B_2)H. Person et.al. (1984) Science 225 687-693 |
| Protein number | see ncbi |
| Warnings | This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Test | Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain. |
| Latin name | Mus musculus |