Mouse anti pS2 Estrogen-Regulated Protein

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Main information

NameMouse anti pS2 Estrogen-Regulated Protein
Catalog numberX1440M
Size100 μg
Price€ 500.00

More details

CategoryPrimary Antibodies
Long descriptionIt recognizes a polypeptide of 6.5kDa which is identified as pS2 estrogen-regulated protein. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy._x000B__x000B_
Antibody come fromHybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP3 receptor protein and mouse myeloma cells.
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
Antigen-antibody binding interactionMouse anti pS2 Estrogen-Regulated Protein Antibody
Antibody is raised inMouse
Antibody's reacts withHuman
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
ApplicationImmunohistochemistry (Paraffin & Frozen Sections)
Antibody's suited forThis antibody can be used for Western blot analysis (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Relevant references1. Strong, P. et al. Prostanoid-induced inhibition of lipolysis in rat isolated adipocytes: Probable involvement of EP3 receptors. Prostaglandins 1992, 43, 559-566_x000B__x000B_2. Coleman, R.A., et al. Classification of prostanoid receptors: Properties, distribution and structure of the receptors and their subtypes. Pharmacol. Rev. 1994, 46, 205-229_x000B__x000B_3. Zeng, L., et al. Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor. J. Biol. Chem. 1996, 271, 27744-27760_x000B__x000B_4. Beiche, F., et al. Localization of cyclooxygenase-2 and prostaglandin E2 receptor EP3 in the rat lumbar spinal cord. J. Neuroimmunol. 1998, 89, 26-34_x000B__x000B_5. Bhattacharya, M., et al. Nuclear prostaglandin receptors. Gene Ther. Mol. Biol. 1999, 4, 323-338_x000B__x000B_6. Morath, R., et al. Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3 and EP4 in human kidney. J. Am. Soc. Nephrol. 1999, 10, 1851-1860_x000B__x000B_7. Nakamura, K., et al. Immunohistochemical localization of prostaglandin EP3 receptor in the rat hypothalamus. Neurosci. Lett. 1999, 260, 117-120_x000B__x000B_8. Nakamura, K., et al. Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups: a double immunoflourescence study in the rat brain. Neuroscience 2001, 103, 763-775
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus