Mouse anti V-CAM-1 (CD106)

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Main information

NameMouse anti V-CAM-1 (CD106)
Catalog numberX1474M
Size100 μg
Price€ 468.00


More details

CategoryPrimary Antibodies
Long descriptionRecognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular and interfollicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin 4 1 (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
Antibody come fromSynthetic peptide derived from the rat Kv1.1 potassium channel conjugated to KLH
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
Clone1.4C3
Antigen-antibody binding interactionMouse anti V-CAM-1 (CD106) Antibody
Antibody is raised inMouse
Antibody's reacts withHuman
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
ApplicationImmunohistochemistry
Antibody's suited forThis antibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Storage-20ºC
Relevant references1. Baumann,A et.al Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems. EMBO J. 7 (8), 2457-2463 (1988)_x000B__x000B_2. Christie,M.J et.al. Expression of a cloned rat brain potassium channel in Xenopus oocytes_x000B_Science 244 (4901), 221-224 (1989)_x000B__x000B_3. Hatton WJ, et.al Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal. J Physiol 2001 Jun 1 533:Pt 2 315-27(2001) _x000B__x000B_4. Wang FC et.al alpha subunit compositions of Kv1.1-containing K+ channel subtypes fractionated from rat brain using dendrotoxins. Eur J Biochem Jul 263:1 230-7 (1999)_x000B__x000B_5. Folco E, et.al A cellular model for long QT syndrome. Trapping of heteromultimeric complexes consisting of truncated Kv1.1 potassium channel polypeptides and native Kv1.4 and Kv1.5 channels in the endoplasmic reticulum J Biol Chem Oct 17 272:42 26505-10 (1997) _x000B__x000B_6. Roberds,S.L Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart Proc. Natl. Acad. Sci. U.S.A. 88 (5), 1798-1802 (1991)_x000B_
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus