Mouse anti Chromosome Associated Protein-E

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Main information

NameMouse anti Chromosome Associated Protein-E
Catalog numberX1485M
Size100 μg
Price€ 304.00


More details

CategoryPrimary Antibodies
Long descriptionCAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.
Antibody come fromSynthetic peptide derived from the rat Kv1.6 potassium channel conjugated to KLH
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
CloneE1M
Antigen-antibody binding interactionMouse anti Chromosome Associated Protein-E Antibody
Antibody is raised inMouse
Antibody's reacts withHuman
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
ApplicationWestern Blot
Antibody's suited forThis antibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Storage-20ºC
Relevant references1. Grupe,A et.al 'Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel family' EMBO J. 9 (6), 1749-1756 (1990)_x000B__x000B_2. Swanson, R et.al 'Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain' Neuron 4 (6), 929-939 (1990)_x000B__x000B_3. Smart SL, et.al 'Identification of the delayed rectifier potassium channel, Kv1.6, in cultured astrocytes.' Glia (United States), , 20(2) p127-34(1997)_x000B__x000B_4. Schmidt K, et al. 'Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors.' Brain Res (Netherlands), , 843(1-2) p145-60(1999)_x000B_
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus