Mouse anti EGFR

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Main information

NameMouse anti EGFR
Catalog numberX1568M
Size100 μg
Price€ 500.00


More details

CategoryPrimary Antibodies
Long descriptionEGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor- (TGF- ), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Antibody come fromUnique peptide sequence derived from the D1 blade of the G 5 protein.
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
CloneH11
Antigen-antibody binding interactionMouse anti EGFR Antibody
Antibody is raised inMouse
Antibody's reacts withHuman doens not react with mouse and rat. Others not known.
Antibody's reacts with these speciesThis antibody doesn't cross react with other species
Antibody's specificityNo Data Available
ApplicationWB of Extracellular domain, FC, IF, IP (native only), IHC (Paraffin)
Antibody's suited forAntibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Storage-20ºC
Relevant references1. Liang, J.J., et al. 'RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat and influence on Gbeta5gamma2-mediated PLCbeta signaling.' J. Neurosci. Res. 2000: 60, 58-64_x000B__x000B_2. Cabrera, J.L., et al. 'Identification of the Gbeta5-RGS7 protein complex in the retina.' Biochem Biophys Res Commun. 1998: 249, 898-902_x000B__x000B_3. Watson, A.J., et al. 'A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina.' J. Biol. Chem. 1996: 271, 28154-28160
Protein numbersee ncbi
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin nameMus musculus