anti-AKT2 Antibody

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Main information

Nameanti-AKT2 Antibody
Catalog number48-432
Size0.05 mg
Price€ 180.00


More details

Gene infoAKT2 encodes a RAC/AKT-type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signalling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism. It is activated by a variety of growth factors. AKT2 has been shown to be transcriptionally regulated by MyoD and to activate MyoD-myocyte enhancer binding factor-2 (MEF2) transactivation activity during muscle differentiation. Glycogen synthase kinase 3 (GSK-3) also has been shown to be a downstream target of AKT2. The AKT2 gene is one of the human homologues of v-akt, the transduced oncogene of the AKT8 virus, which induces lymphomas in mice. It has been implicated in breast, ovarian, and pancreatic cancers.
Gene namesAKT2, PKB beta, PKBBETA, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-PK-beta, Rac protein kinase beta, RAC-BETA, HIHGHH, PKBB
Antibodie's labelunlabelled serum
Ab raised inRabbit
TypePolyclonal
AntigenAKT2 antibody was made against a peptide corresponding to the C-Terminus of AKT2 (Human).
Immuno applicationWestern Blot, immuno-histo-chemistry, immuno precipitation
Antibody adviceAKT2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.
Suspention, pH, azidePBS, 0.05% sodium azide.
Keep atStore AKT2 antibody at 4 grades C, Avoid Freezing
Works withHuman, Mouse, Rat
Omim nr1170703
Ncbi nrP31751
Vial with antibodyin solution
NCBI GENE nr208
GENE symbolAKT2
Antigene namev-akt murine thymoma viral oncogene homolog 2
SourceHomo sapiens
Protein nrP31751
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps