anti-RAF1 Antibody

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Main information

Nameanti-RAF1 Antibody
Catalog number48-711
Size0.05 mg
Price€ 180.00


More details

Gene infoRAF, a member of the Raf Subfamily of Serine/Threonine Protein Kinases, is part of the RAS-dependent signalling pathway. Once activated, Raf-1 can activate the dual specificity protein kinases MEK1 and MEK2 which in turn activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. t(3;8)(p25;q21) translocations involving RAF1 result in mixed parotid gland tumors. Raf1 is an ocogene that has been reported to be overexpressed in many tumor types.
Gene namesRAF1, C-Raf, C-raf-1, CRAF, NS5, Raf-1, Proto-oncogene c-RAF, Oncogene RAF1, RAF, Raf1 kinase
Antibodie's labelunlabelled serum
PurityImmunoaffinity Chromatography
Ab raised inRabbit
TypePolyclonal
ImmunoglobulinIgG
Spicific topSer259
AntigenRAF1 antibody was made against amino acids surrounding Ser 259 of RAF1 (Human).
Immuno applicationWestern Blot, immuno-histo-chemistry
Antibody adviceRAF1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200.
Suspention, pH, azidePBS, 0.02% sodium azide, 50% glycerol.
Keep atRAF1 antibody should be stored long term (months) at -80 grades C and short term (days) at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
Works withHuman, Mouse, Rat
Omim nr125651
Ncbi nrP04049
Vial with antibodyin solution
NCBI GENE nr5894
GENE symbolRAF1
Antigene namev-raf-1 murine leukemia viral oncogene homolog 1
SourceHomo sapiens
Protein nrP04049
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps