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| Name | anti-ABL2 Antibody [1H1B11] |
|---|---|
| Catalog number | 32-104 |
| Size | 0.1 mL |
| Price | € 180.00 |
| Gene info | ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization，c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. |
|---|---|
| Gene names | ABLL, ARG, Abelson murine leukemia viral oncogene homolog 2ARG, ABLL |
| Antibodie's label | unlabelled serum |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 1H1B11 |
| Immunoglobulin | IgG1 |
| Antigen | Ni-NTA purified truncated recombinant ABL2 expressed in E. Coli strain BL21 (DE3). |
| Immuno application | ELISA, Western Blot, immuno fluorescence |
| Antibody advice | DilutionWestern Blot:1:200 - 1:1,000 IF:1:100 - 1:500ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test. |
| Suspention, pH, azide | Ascitic fluid containing 0.03% sodium azide. |
| Keep at | ABL2 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Works with | Human |
| Omim nr | 1168268 |
| Ncbi nr | P42684 |
| NCBI GENE nr | 27 |
| GENE symbol | ABL2 |
| Antigene name | c-abl oncogene 2, non-receptor tyrosine kinase |
| Source | Homo sapiens |
| Protein nr | P42684 |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Properties | If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation | anticorps |