anti-AKT1 Antibody

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Main information

Nameanti-AKT1 Antibody
Catalog numberXW-7019
Size0.05 mg
Price€ 180.00


More details

Gene infoSerine/threonine protein kinase; Murine thymoma viral (v-akt) oncogene homolog-1. AKT1 is a serine-threonine protein kinase. It is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Gene namesPKB, RACProtein kinase B, PKB, AKT, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA,
Antibodie's labelunlabelled serum
PurityAntigen affinity-purified
Ab raised inChicken
TypePolyclonal
Antigen2-200
Immuno applicationWestern Blot
Antibody adviceAKT antibody can be used for the detection of AKT by Western blot, may also work for IHC and ICC.
Suspention, pH, azidePhosphate-Buffered Saline. No preservatives added.
Keep atAKT1 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Works withHuman, Mouse, Rat, Bovine, Xenopus
Omim nr4885061
Ncbi nrNP_005154.1
KDa55.7 kDa (calculated)
Vial with antibodyin solution
Quantity per ml1 mg/mL
NCBI GENE nr207
GENE symbolAKT1
Antigene namev-akt murine thymoma viral oncogene homolog 1
SourceHomo sapiens
Protein nrP31749
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps