Here you can find detailed information about selected products. Contact with us if you have nay questions to product or order proces.
| Name | anti-AKT1 Antibody |
|---|---|
| Catalog number | XW-7019 |
| Size | 0.05 mg |
| Price | € 180.00 |
| Gene info | Serine/threonine protein kinase; Murine thymoma viral (v-akt) oncogene homolog-1. AKT1 is a serine-threonine protein kinase. It is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. |
|---|---|
| Gene names | PKB, RACProtein kinase B, PKB, AKT, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA, |
| Antibodie's label | unlabelled serum |
| Purity | Antigen affinity-purified |
| Ab raised in | Chicken |
| Type | Polyclonal |
| Antigen | 2-200 |
| Immuno application | Western Blot |
| Antibody advice | AKT antibody can be used for the detection of AKT by Western blot, may also work for IHC and ICC. |
| Suspention, pH, azide | Phosphate-Buffered Saline. No preservatives added. |
| Keep at | AKT1 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Works with | Human, Mouse, Rat, Bovine, Xenopus |
| Omim nr | 4885061 |
| Ncbi nr | NP_005154.1 |
| KDa | 55.7 kDa (calculated) |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 207 |
| GENE symbol | AKT1 |
| Antigene name | v-akt murine thymoma viral oncogene homolog 1 |
| Source | Homo sapiens |
| Protein nr | P31749 |
| Description | This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. |
| Properties | If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation | anticorps |